Cardiac Surgery (Adult)

We conduct a wide range of studies in adult cardiac surgery. Some look at aspects of surgery itself, and some look at drug interventions. These interventions can be applied before, during and after cardiac surgery. Drug interventions could also take the form of fluid replacement immediately prior to surgery, medication added to the cardiopegia solution used to stop the heart during surgery or insulin control of glucose levels during or after surgery.

Other interventions we have investigated include midline incision versus rib incision for coronary bypass surgery, cooling the body during surgery and comparing alternative methods of taking the vein for grafting and testing its viability. 

Cardiac Surgery (Children)

The child cardiac surgery studies are designed to improve outcomes after cardiac surgery for congenital heart conditions and are important as evidence gathered in adult cardiac surgery trials cannot always be extrapolated to children. 


Our cardiology portfolio is diverse, ranging from studies looking at the best way to diagnose cardiac disease to management of drug therapy after treatment for a blocked coronary artery using angioplasty. 

Emergency Medicine

Trials of interventions to be used in emergency care settings, such as equipment or treatment used in ambulances in the management of cardiac arrests. 


Our surgery studies include comparing different surgical methods (e.g. different types of bariatric surgery for the management of morbid obesity) or comparing aspects of the care of surgical patients (e.g. the use of wound dressings in abdominal and obstetric surgery). 



Our ophthalmology studies mainly focus on the treatment and management of neovascular Age related Macular Degeneration, the most common type of blindness in the over 50s.  Studies include looking at the best treatment regimen, and whether the disease requires hospital consultant care or can be managed by community optometrists. 


Our peri-operative studies look at interventions during the peri-operative period. 


Rare Diseases

Studies of treatment for rare diseases, such a Barth syndrome, a genetic disease.

Respiratory Medicine 

Our study in respiratory medicine looks at the thickening of the lungs caused by asbestos, and the best ways to scan for cancer. 

Thoracic Surgery

Our thoracic surgery studies investigate surgical procedures of the heart, lungs, oesophagus, and other organs in the chest.

Completed Studies 

This section documents studies which the CTEU have coordinated, and from which the results have been published.